Sitapur (Uttar Pradesh): Eight persons were killed and more than 24 injured when a milk tanker hit a tractor trolley here. The accident took place on Monday night on the Sitapur Lakhimpur road in the Kotwali police circle. All the passengers of the tractor trolley were going to attend a wedding to Machrehata. Six persons died on the spot while more than two dozen were seriously injured in the accident. Some of the critically injured persons were reffered to the Trauma Centre in Lucknow. All the deceased persons are residents of Dalwal village under Kotwali area. Superintendent of Police L.R. Kumar said that while the administration and police rushed to the District Hospital after the accident, people created a ruckus after which PAC personnel were deployed at the hospital.
Shahjahanpur (UP): At least 17 people, including three children, were killed and four injured when a speeding truck rammed into two vehicles before overturning on one of them in Uttar Pradesh’s Shahjahanpur district on Tuesday morning, police said.The accident occurred at the Jamka crossing on National Highway 24 near Shahjahanpur town, 170 km northwest of Lucknow, Superintendent of Police (City) Dinesh Tripathi said. It was a series of collisions, police recounted. The speeding truck first hit a tempo and then a van, which fell into a ditch. The truck then overturned and fell on the van, trapping those inside it. Also Read – Uddhav bats for ‘Sena CM’The impact was so powerful that 16 people, including three children aged between 6-12, died instantly. A woman died of her injuries on the way to a hospital, the officer said. A crane was sent from Shahjahanpur to lift the mangled truck and retrieve the bodies. The truck driver fled the spot, while the helper has been nabbed, the SP said. The tempo was ferrying passengers from Bartara, while the van was carrying passengers from Shahjahanpur. The injured were admitted to a local hospital and the bodies have been sent for post-mortem, the SP said. Also Read – Farooq demands unconditional release of all detainees in J&KThe deceased have been identified as Aman (6), Alia (8), Arshit (12), Azim (26), Balram (40), Vinod (40), Ram Kishore (48) and Budha Lal (46), the officer said, adding that efforts were on to identify the remaining victims. Bareilly division commissioner Ranvir Prasad said a magisterial inquiry would be conducted to ascertain if the accident was a result of the truck driver’s laxity or any problem in the vehicle. He said it would also be probed if the vehicles ferrying passengers had valid permit. Prasad and Deputy Inspector General Rajesh Kumar Pandey visited the accident site and also the hospital to enquire about the health of the injured. Chief Minister Yogi Adityanath expressed condolence over the deaths. He has directed officials to extend proper medical care to the injured and ensure ex-gratia payment as per the rules to the next of kin of the deceased, an official said.
Rabat – A young man working as a “Cireur”, or shoeshine boy, attempted to immolate himself on Saturday evening inside the police station at Avenue Hassan II in Casablanca, after he was arrested for sniffing glue and paint thinner.The 21-year-old shoeshine boy, poured paint thinner on his body and set himself on fire using a lighter.According the authorities, the police extinguished the fire, but his legs were burned. The police took the victim to the hospital to receive necessary aid. The same source added that during the investigation, it was revealed that the shoeshine boywas just released from prison on October 25 after completing a five-year sentence for being involved with a murder, along with his brother.The young man told the police that he has tried to commit suicide 25 times and he attempted to hang himself in his cell when he was in prison.
The “World Electronic Media Forum” is a special event organized by the UN Department of Public Information (DPI) along with the European Broadcasting Union (EBU) and Switzerland in conjunction with the World Summit on the Information Society (WSIS), which will run from 10 to 12 December. The Forum, scheduled for 9 to 11 December, will be seen live by satellite around the world and include real-time contributions from several continents by television and over the internet. Panels, workshops and keynote speeches will explore the enhanced role of media in the information society, and examine such key topics as universal access to information, freedom of expression, cultural diversity, economic development, social cohesion and education. Using the resources of the EBU, NHK and the Swiss Broadcasting Corporation, the Forum will showcase the technological possibilities of modern media and be broadcast live by satellite and on the Internet. Satellite video links will bring together participants from a variety of locations around the world to interact with those in Geneva. The Forum will also feature originally produced audiovisual materials and a web site in nine languages, including the UN’s six official languages. UN Secretary-General Kofi Annan and the Swiss President Pascal Couchepin are scheduled to open the Forum, which will be an important opportunity for media professionals from the developing world to meet and exchange views with their counterparts from industrialized countries.
The initiative, called “Alliance of Civilizations,” is intended “to respond to the need for a committed effort by the international community – both at the institutional and civil society levels – to bridge divides and overcome prejudice, misconceptions, misperceptions, and polarization which potentially threaten world peace,” Mr. Annan’s spokesman said in a statement at UN Headquarters in New York.The call for the alliance was initiated by Spanish Prime Minister José Luis Rodriguez Zapatero and co-sponsored by Turkish Prime Minister Recep Tayyip Erdogan. Mr. Annan called on the international community to contribute to a trust fund to support the Alliance. “The Alliance will aim to address emerging threats emanating from hostile perceptions that foment violence, and to bring about cooperation among various efforts to heal such divisions,” the statement said.“Events of recent years have heightened the sense of a widening gap and lack of mutual understanding between Islamic and Western societies – an environment that has been exploited and exacerbated by extremists in all societies,” it added.“The Alliance of Civilizations is intended as a coalition against such forces, as a movement to advance mutual respect for religious beliefs and traditions, and as a reaffirmation of humankind’s increasing interdependence in all areas – from the environment to health, from economic and social development to peace and security.”In answer to questions at the daily noon briefing spokesman Stéphane Dujarric said the initiative was not “linked in the calendar” to last week’s terrorist attacks in London that killed more than 50 people and injured 700 or to other attacks, adding that the two prime ministers had been working on it for some time.“But I think any initiative that can help bridge understanding between civilizations and especially between the Western world and the Islamic world is very much a welcome one,” he declared.The statement said the Spanish and Turkish governments would continue, as co-sponsors, to provide support and several other Governments and organizations had expressed interest in joining them.“The Secretary-General hopes that more will do so,” it added. “The co-sponsors have already pledged substantial initial contributions to a Trust Fund set up to finance the initiative, and the Secretary-General will be inviting other governments and entities to contribute.”Mr. Annan is bringing together a high-level group of eminent persons to guide the initiative. The group is expected to present a report with recommendations and a practical plan of action in late 2006.
KANSAS CITY, Mo. – H&R Block Inc. posted a smaller loss in its fiscal second quarter than a year ago, when the tax preparer booked a bigger loss from operations that have since been discontinued.The Kansas City, Mo., company typically reports a loss in the August-October period because it takes in most of its revenue during the U.S. tax season.Bill Cobb, H&R Block’s president and CEO, said he’s confident that the company is well-positioned to deliver strong results this year as the company wades into the upcoming tax season.The nation’s largest tax-preparation company benefited in the latest quarter from growth in interest income and product and other revenue. But service revenue declined from a year ago, primarily because of timing differences in the company’s Australian operations.Operating expenses grew to roughly $315 million from $302.3 million a year earlier, driven by higher compensation and benefits, as well as selling, general and administrative costs.Cobb also noted that the company has made progress in its goal of divesting itself from its banking arm. Investors will be looking for more details on that on Wednesday morning, when the company is scheduled to discuss its latest financial results during a conference call with Wall Street analysts.Block agreed in July to sell its H&R Block Bank assets to Republic Bank and Trust Co., a subsidiary of Republic Bancorp Inc. As a condition of the deal, Republic applied with regulators to convert into a national bank, but ultimately withdrew its application. As a result, Block terminated its agreement with Republic in October.Block has said it remains committed to no longer being regulated a savings and loan holding company by the Federal Reserve and partnering with a lender to expand its financial services business.All told, Block reported a loss of $104.9 million, or 39 cents per share, for the three months ended Oct. 31. That compares with a loss of $105.2 million, or 39 cents per share, a year earlier.Block’s adjusted loss amounted to 38 cents per share.Analysts polled by FactSet anticipated a loss of 37 cents per share.Revenue slipped to $134.3 million, from $137.3 million.Analysts had forecast $137.9 million in revenue.Shares ended regular trading down 22 cents at $28.80. The stock slipped another 30 cents, or 1 per cent, to $28.50 in extended trading. Tax prepare H&R Block posts slightly smaller 2Q loss, dip in revenue AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by The Associated Press Posted Dec 10, 2013 3:07 pm MDT
Amid reports that 130 people have been shot dead by security services across the country since the “zero-tolerance” policy began on 15 May, the UN High Commissioner for Human Rights said that he was “gravely concerned” that “such a large number of people” have been killed.In his appeal to the government of Bangladesh, Zeid described official declarations that none of the victims was innocent as “dangerous…and indicative of a total disregard for the rule of law”.Everyone has the right to life, the High Commissioner continued in his statement, and people “do not lose their human rights, because they sell drugs”.In addition to those allegedly killed in the anti-narcotics drive, 13,000 people have also been reportedly arrested.Such a high number of detentions indicates “a high likelihood” that many have been detained arbitrarily, the top UN official said.Every person has the right to life. People do not lose their human rights because they use or sell drugs – UN human rights chief, Zeid Ra’ad Al HusseinIn his statement to the government of Bangladesh – where elections are to be held later this year – Zeid noted that there was “no doubt” that drug sales and trafficking caused “tremendous suffering for individuals and entire communities”.And while commending the country for its “tremendous support” for hundreds of thousands of Rohingya refugees who fled violence in neighbouring Myanmar since August last year, the UN High Commissioner insisted that “extrajudicial killings, arbitrary arrests and the stigmatization (of drug-users) cannot be the answer”.The High Commissioner urged the authorities to investigate the alleged extra-judicial killings, stressing that there must be no impunity for human rights violations in the name of drugs control policies.His comments follow Bangladesh’s participation in a scheduled review of the country’s human rights record at the UN in Geneva in early May.At that Universal Periodic Review meeting, Bangladesh’s minister for Law, Justice and Parliamentary Affairs said that official inquiries would take place into other alleged extrajudicial killings in the country.
Valve has been looking at the use of biometrics in games for quite a while now, and they even have an experimental psychologist on staff in the form of Mike Ambinder. He was present at the NeuroGaming Conference and Expo last week to talk about what exactly Valve is trying to achieve with biofeedback, and how it involves gamer sweat and eye movement.The issue Valve sees at the moment with games is that they can’t detect a player’s emotional state. If they could, then the gameplay could react to enhance the experience and potentially make it more enjoyable. So Valve started experimenting with biofeedback, more specifically, they’ve been detecting the pH level of a player’s sweat through skin conductance in order to figure out how calm or nervous they are during play.That information has been fed into a build of Left4Dead where a mission asks the player to kill 100 enemies in 4 minutes. Monitoring the ph level in the sweat sees the game react to someone who is nervous by speeding up gameplay. Players who remain calm have the gameplay speed remain normal.In a similar vein Portal 2 has been patched to allow for control using the player’s eye movement, allowing them to aim with their eyes instead of with their hands. The end result works surprisingly well, but must surely take a bit of getting used to.The experiment is set to continue as well as being expanded to other types of feedback such as heart rate, overall body temperature, and even the expression on your face. It isn’t limited to just impacting gameplay, either. Such biofeedback could be used to better match players for multiplayer games.
Facebook Twitter: @NeosKosmos Instagram The process of counting the votes for European Parliament candidates was due to be completed over the weekend, with the 21 MEPs that will represent Greece and their parties appearing to have been decided from Friday.SYRIZA has elected six parliamentarians: Manolis Glezos (photo), Sofia Sakorafa, Dimitris Papadimoulis, Constantina Kuneva, Giorgis Katrougalos and Constantinos Chrysogonos.New Democracy will be represented by five MEPs: Manolis Kefaloyiannis, Maria Spyraki, Eliza Vozemberg, Giorgos Kyrtsos and Theodoros Zagorakis.Golden Dawn’s three European lawmakers will be Eleftherios Synadinos, Lambros Fountoulis and Giorgos Epitideios.The PASOK-led Elia alliance elected Eva Kaili and Nikos Androulakis.To Potami is sending Giorgos Grammatikakis and Miltiadis Kyrkos to the European Parliament.Constantinos Papadakis and Sotiris Zorianopoulos will represent the Greek Communist Party.Independent Greeks’ sole representative will be Notis Marias.Glezos, a World War II hero who has already served a term in Brussels and Strasbourg, was due to gather some 400,000 votes, making him by far the most well-supported candidate.
Insecte : la découverte du plus vieux fossile fait l’objet d’analysesUne étude parue dans Proceedings of the National Academy of Sciences analyse les techniques de déplacement des insectes de la période du carbonifère, il y a environ 300 millions d’années. Pour ce faire, les chercheurs ont étudié le plus vieux fossile d’insecte découvert en 2008 dans le Massachusetts.Le fossile analysé dans l’étude est incroyablement bien conservé. Découvert en 2008 par des chercheurs de l’Université Tufts, l’empreinte d’environ 7,6 centimètres de long comporte le thorax, l’abdomen et les six pattes de l’insecte. Son aspect général se rapproche très fortement de celui d’un éphémère actuel. Cette comparaison laisse penser qu’il existait déjà au carbonifère une forme archaïque de l’insecte ayant vécu il y a 300 millions d’années.Le fossile découvert représente la plus ancienne trace du passage d’un insecte, un exploit pour des espèces de ce type dont le corps, trop fragile, n’est pas propice au processus de fossilisation. Trois ans après la réalisation de cette fabuleuse trouvaille, une étude parue dans Proceedings of the National Academy of Sciences analyse l’empreinte pour tenter de comprendre le déplacement de cette espèce. A première vue, il est possible de constater que la trace faite par l’insecte ne présente aucune aile. Cette absence suggère que l’empreinte a été effectuée suite à un atterrissage sur une nappe de boue. Selon les scientifiques, cet atterrissage peut être dû à deux types de causes. À lire aussiIl laisse une fourmi coupe-feuille lui découper le doigtLa première, directement liée aux techniques de vol, suggère que ces insectes du carbonifère se déplaçaient en rasant des plans d’eau pour se poser sur des espaces boueux, capables de supporter leur poids. La deuxième hypothèse suppose que l’insecte aurait pu glisser en s’approchant de la flaque de boue. Il est pour le moment impossible pour les scientifiques de trancher entre les deux suppositions et les techniques de vol des insectes archaïques restent encore en suspens. Les insectes représentaient déjà, il y a 300 millions d’années, une classe largement répandue sur Terre, bien avant l’apparition des premiers ancêtres des dinosaures. Le 17 avril 2011 à 17:44 • Emmanuel Perrin
New Real Madrid signing Vinicius Junior declares he is prepared to challenge for a first-team place at the club after signing from Flamengo.Madrid is ready to loan out the 18-year-old in order to help his first-team development, but the Brazilian insists this will not be necessary.“I have come to be a part of Madrid’s first team,” Vinicius told reporters on Friday via Football Espana.“I will play for the Castilla initially to adapt and then move as quickly as possible, I believe this move will help me become a much better player.“There will be a lot of pressure here of course but there was also plenty of pressure at Flamengo, so I must be able to adapt quickly and the aim is to win as much as possible.Zidane reveals Sergio Ramos injury concern for Real Madrid Andrew Smyth – September 14, 2019 Zinedine Zidane has put Sergio Ramos’ availability for Real Madrid’s trip to Sevilla next weekend in doubt after withdrawing him against Levante.“I will need to learn a lot here and also make many sacrifices, but these values have been instilled in me from my family.“Neymar is my idol, I follow him really closely, it is the same for everyone in Brazil, he is someone to look up to and someone who has led the nation for the past few years.“I do not know if I am similar to him or not, or if I have the potential to be better, that is up for you guys (the press) to say.“I have come to Real Madrid to work hard and become an important player for this club.”
Halfway through the trial, a judge on Monday afternoon dismissed an open public meetings lawsuit against Clark College filed by two former students.The suit was filed by former students Marcus Griffith, 29, and Jasmine Bhullar, 21. It alleged that a student council of the state community college held private, not public, meetings after Griffith and Bhullar registered complaints about the Spring 2009 student government elections. The state Open Public Meetings Act generally requires agencies to hold public meetings, but contains a list of exceptions.Clark County Superior Court Judge Roger Bennett said the plaintiff’s allegations reflected a misinterpretation of the law. The college’s attorney, Bonnie Terada, asked for the dismissal after the plaintiffs’ attorney, April Boutillette Brinkman, presented her case.Bennett agreed. “My ruling was that that was flat out not the law,” the judge said in his chambers afterward.Bennett sided with the college, which argued that the Associated Students of Clark College’s executive council meetings were exempt from the public meetings law because they were quasi-judicial, or a hearing where a council was applying existing policies. The students’ attorney had argued the council was making policies. The judge also tossed out allegations that the executive council did not give proper public notice when it decided to discipline and then dismiss Bhullar from her post as an ASCC executive assistant. He said the law doesn’t outline that a council needs to address that specific action in a public meeting.Following the judge’s decision, Brinkman said her clients were disappointed, and wished a jury had been able to decide the case. But open public meeting law cases in Washington are decided by a judge.
“It’s illegal,” said driver Bryant Grosso, “so I mean, if the police need to be policed, that’s a problem.”The Florida Department of Highway Safety and Motor Vehicles, FHP’s parent agency, reacted with a state-wide warning to command staff.“It is more important than ever before that FHP be proactive in their efforts, but members should never be encouraged to meet specific citation numbers. I am directing you to ensure that no quotas are being issued from our troops and that no performance metrics are impacted by a quota,” said Florida DHSMV Executive Director Terry Rhodes.A program in Miami-Dade has been canceled as of late last week. Some troopers have been rewarded with not having to work as many weekends because of so-called “high activity,” and ticket-writing was included in that measurement.Florida DHSMV Communications Director Beth Frady spoke to 7News about the program by phone.“There were no quotas as part of that program. No additional days off were provided. No additional cost to tax payers resulted,” said Frady. “It was merely switching their days.”Frady also said the program was canceled so that they don’t give the wrong impression. MIAMI (WSVN) – Florida Highway Patrol officers in Miami-Dade were rewarded with time off for writing tickets, according to a joint report by the Miami Herald and the Times Tallahassee Bureau.The report revealed that state officials are examining practices in which FHP officers around the state are being rewarded for writing tickets. Troopers in Miami-Dade are reported to be granted the choice of weekends off based of their performance.Troopers said a memo issued by a captain at FHP praised the work of several officers and stated, “Sergeants, please get with these members and schedule their weekend pass.”This comes to light after state officials confirmed a high-ranking FHP official told troopers to write two tickets per hour to justify a pay raise.“Just because they wanna reach the limit, they shouldn’t,” said one driver.“I hate to think that they’re out there just targeting people, but hopefully not,” said driver Bond Oman.Florida law prohibits law enforcement agencies from establishing traffic citation quotas. “I break that law, I’m gonna be ticketed,” said Grosso, “so what happens to the people that allow this to happen?”An FHP union leader said he is waiting to see what is going to happen in North Florida and if there will be a punishment.Copyright 2019 Sunbeam Television Corp. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
WILMINGTON, MA — Below is a round-up of what’s going on in Wilmington on Thursday, May 31, 2018:Happening Today:Weather: Mostly sunny, with a high near 80. Light south wind increasing to 6 to 11 mph in the morning.In The Community: The Wilmington High School Baseball team is holding a fundraiser at Jake n Joes Bar & Grille (230 Mishawum Road) in Woburn on Thursday, May 31, 2018, from 11:30am to close (12:30am Friday). Bring this flyer and 20% of your bill will be donated to the WHS Baseball program. Applies to dine-in and take-out only, not delivery.In The Community: Do you like to sing? Do you enjoy performing? Come join the Merrimack Valley Chorus at one of its regular weekly rehearsals. You just might discover a passion for a cappella singing, and you’ll also make some great new friends! Open rehearsals are every Thursday at 7pm at the Wilmington Arts Center (219 Middlesex Avenue).At The Library: Going Native: Low Maintenance Trees and Shrubs at 7pm. [Learn more and register HERE.]At The Senior Center: Computer Class at 9:15am. Art Class at 10am. Aerobics at 10:30am. Knitting/Crocheting at 11am. Ceramics at 1pm. Game Day at 1pm. Stress Management at 1pm. Mabel & Jerry Performance at 1pm. [Learn more HERE.]At The Town Museum: The Wilmington Town Museum is open from 10am to 2pm.Live Music: Larry Gilbert performs at Rocco’s Restaurant & Bar (193 Main Street) beginning at 6pm. … Pianist Ricky Lauria performs at Tremezzo (2 Lowell Street) at 8pm.Go Wildcats!: 3 WHS teams are in action today. See the complete schedule HERE.(NOTE: What did I miss? Let me know by commenting below, commenting on the Facebook page, or emailing firstname.lastname@example.org. I may be able to update this post.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email email@example.com.Share this:TwitterFacebookLike this:Like Loading… RelatedThe Wilmington Insider For August 23, 2018In “5 Things To Do Today”The Wilmington Insider For August 16, 2018In “5 Things To Do Today”The Wilmington Insider For January 11, 2018In “5 Things To Do Today”
(Phys.org) —A fundamental question in the evolution of animal body plans, is where did the head come from? In animals with a clear axis of right-left symmetry, the bilaterians, the head is where the brain is, at the anterior pole of the body. Little is known about the possible ancestor of bilaterians. Fortunately their sister group from that same progenitor, the cnidarians, can be studied in parallel today to give some clues. Cnidarians are creatures like jellyfish, hydra, and sea anemone which possess rudimentary nerve nets, but no clear brain. They all have just a single orifice to the external world, which basically does it all. In a recent paper published in PLOS Biology, researchers from the University of Bergen in Norway compared gene expression patterns in sea anemone (Nematostella vectensis, Nv) with that from a variety of bilaterian animals. They found that the head-forming region of bilaterians is actually derived from the aboral, the opposite-oral, side of the ancestral body plan. Pioneering developmental biologist Lewis Wolpert, is often credited with having observed: “It is not birth, marriage, or death, but gastrulation which is truly the most important time in your life.” Almost all animals undergo a similar gastrulation process early in their development. The point where the cells first invaginate during gastrulation, the blastopore, uniquely defines an embryonic axis. After this stage however, all bets are off—attempts to define phyla according to hardline criteria, like blastopore = anus, are invariably met by counterexample where it instead becomes the mouth. Gene expression, while not always constrained into single contiguous areas, therefore provides a baggage-free way to assign homology across species.Wolpert’s concept of positional information in development has been largely vindicated by the discovery of hox gene codes in a wide variety of animals. While hox genes are the critical regulators of axial patterning, in most bilaterians they are not expressed in the anterior head-forming region. The researchers focused instead on the genes six3 and FoxQ2, transcription factors which have been shown to regulate anterior-posterior development. Six3 knockouts in mice, for example, fail to develop a forebrain. In humans six3 regulates forebrain and eye development.Sea anemone, like Nematosella, are curious creatures. As larvae they swim about with their aboral pole forward. As adults they plunge this region into the sea floor, and permanently anchor themselves in. Their bodies then undergo various changes but their oral pole remains intact for feeding. By using knockdown and rescue experiments in Nemostella, the researchers were able to show that six3 is required for the development of the aboral region, and the expression of further regulatory genes. This suggests that the region distal from the cnidarian mouth parallels development of the bilaterian head. The researchers also looked at the expression of the forkhead domain protein foxQ2, which functions downstream of six3. Forkhead box genes are an important class of transcription factors which frequently lack the signature homeodomains and zinc-finger regions common to other transcription factors. Instead they have a unique DNA-binding region that has the shape of a winged helix. The forkhead gene, fox2p, in humans has recently garnered a lot of media attention for its apparent role in neural development, and in even more esoteric functions like speech development. FoxQ2 is known to be a well-conserved marker for the most anterior tip of a variety of bilaterians including sea urchines, drosophila, and cephalochordates. The researchers established that before gastrulation in cnidarians, foxQ2a was expressed in the aboral pole, and in a small number cells resembling neurons. Afterwards the expression of this “ring gene” was excluded from a central spot. In conclusion, the expression of genes for anemone head development, away from the mouth region, suggests that head development came first and was a separate event from mouth development. Secondarily, the head and a coalescing brain appear to have merged to become a centralized control center. Where does our head come from? Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2013 Phys.org Journal information: PLoS Biology Citation: Which came first the head or the brain? (2013, March 28) retrieved 18 August 2019 from https://phys.org/news/2013-03-brain_1.html More information: Sinigaglia C, Busengdal H, Leclère L, Technau U, Rentzsch F (2013) The Bilaterian Head Patterning Gene six3/6 Controls Aboral Domain Development in a Cnidarian. PLoS Biol 11(2): e1001488. doi:10.1371/journal.pbio.1001488AbstractThe origin of the bilaterian head is a fundamental question for the evolution of animal body plans. The head of bilaterians develops at the anterior end of their primary body axis and is the site where the brain is located. Cnidarians, the sister group to bilaterians, lack brain-like structures and it is not clear whether the oral, the aboral, or none of the ends of the cnidarian primary body axis corresponds to the anterior domain of bilaterians. In order to understand the evolutionary origin of head development, we analysed the function of conserved genetic regulators of bilaterian anterior development in the sea anemone Nematostella vectensis. We show that orthologs of the bilaterian anterior developmental genes six3/6, foxQ2, and irx have dynamic expression patterns in the aboral region of Nematostella. Functional analyses reveal that NvSix3/6 acts upstream of NvFoxQ2a as a key regulator of the development of a broad aboral territory in Nematostella. NvSix3/6 initiates an autoregulatory feedback loop involving positive and negative regulators of FGF signalling, which subsequently results in the downregulation of NvSix3/6 and NvFoxQ2a in a small domain at the aboral pole, from which the apical organ develops. We show that signalling by NvFGFa1 is specifically required for the development of the apical organ, whereas NvSix3/6 has an earlier and broader function in the specification of the aboral territory. Our functional and gene expression data suggest that the head-forming region of bilaterians is derived from the aboral domain of the cnidarian-bilaterian ancestor.Synopsys: www.plosbiology.org/article/in … journal.pbio.1001484
Cedara I-Response is an application designed to support clinical trials workflows and oncology viewing. I-Response supports key concepts of double-blind reading, registration, advanced segmentation, comparison of multiple time points and support for clinical trial rules. I-Response has three distinct analysis techniques. The base Lesion Analysis package streamlines the clinical trials workflow of creating/exporting the RECIST, WHO and Volume measurements. The PET/CT Analysis package enables users to compare SUV values over multiple time points. The Functional Diffusion Mapping (fDM) Analysis package can track changes in tumors at the metabolic or cellular level over multiple time points. fDM is a patented MR tumor analysis technique. FacebookTwitterLinkedInPrint分享 Technology | October 07, 2008 Cedara I-Response Supports Clinical Trial Workflow, Oncology Viewing
News | Cardiovascular Ultrasound | August 07, 2019 Contrast Use in First Transthoracic Echocardiogram for Heart Failure Reduces Repeat Testing Heart failure is the fourth most common cause for all admission to U.S. hospitals, and it is the most common reason for… read more Ablavar has an MRA indication to evaluate aortoiliac occlusive disease.January 20, 2010 – The first FDA-cleared contrast imaging agent for use with a magnetic resonance angiography (MRA) indication to evaluate aortoiliac occlusive disease (AIOD) and suspected peripheral vascular disease enters the U.S. market today. AIOD is a type of peripheral vascular disease that occurs when arteries, which carry blood from the heart to the lower limbs, become narrowed or blocked. This lack of blood supply can result in pain, infection and even loss of limbs[i]. VIDEO: How Alexa Might Help During Interventional Radiology ProceduresKevin Seals, M.D., is working on a research project using smart speakers such as the Amazon Echo and Google Home to create a new method for accessing information on device technologies in real time in the interventional radiology (IR) lab.Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 4:47Loaded: 3.40%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -4:47 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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Technology | Interventional Radiology | August 14, 2019 FDA Clears NvisionVLE Imaging System for Pancreatic and Biliary Applications August 14, 2019 — NinePoint Medical Inc. announced it has received U.S. read more News | Interventional Radiology | July 03, 2019 Varian Purchasing Embolic Bead Assets from Boston Scientific Varian announced it has signed an asset purchase agreement to acquire the Boston Scientific portfolio of drug-loadable… read more Feature | Contrast Media | July 18, 2019 | By Greg Freiherr How To Manage Risk in the MR Suite Macrocyclic contrast agents have the best safety profile of all the magnetic resonance (MR) contrast media that are n read more News | Interventional Radiology | July 31, 2019 International Multidisciplinary Group Publishes Recommendations for Personalized HCC Treatment With Y90 TheraSphere New consensus recommendations for personalized treatment for hepatocellular carcinoma (HCC) with BTG’s TheraSphere have… read more Two brain metastases from primary lung cancer are contrast enhanced in the brain of a 61-year-old male. Speakers at AHRA 2019 will state that ProHance and other macrocyclic MR agents present a very low risk to patients. Images courtesy of Bracco Image courtesy of NinePoint Medical Technology | Contrast Media | August 05, 2019 Bracco Receives FDA Approval for Varibar Thin Liquid for Oral Suspension Bracco Diagnostics Inc. announced U.S. Food and Drug Administration (FDA) approval for Varibar Thin Liquid (barium… read more In Phase 3 clinical studies, Ablavar, the contrast agent that Lantheus Medical Imaging launched today, demonstrated statistically greater sensitivity (detecting disease when present) compared with noncontrast MRA[ii]. These studies, which supported the U.S. Food and Drug Administration (FDA) approval of Ablavar, show that MRA images using Ablavar provided diagnostic accuracy comparable to conventional X-ray angiography,[iii],[iv] an invasive procedure which involves insertion of a catheter into the arteries in the upper thigh (groin area) or arm[v]. Technology | Interventional Radiology | August 16, 2019 Profound Medical Receives U.S. FDA 510(k) Clearance for Tulsa-Pro Profound Medical Corp. announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to… read more Related Content Technology | Contrast Media | July 15, 2019 FDA Approves Bayer’s Gadavist Contrast for Cardiac MRI in Adult Coronary Artery Disease Patients The U.S. Food and Drug Administration (FDA) has approved Gadavist injection for use in cardiac magnetic resonance… read more Technology | January 20, 2010 First MRA Contrast Agent for AIOD Enters U.S. Market “Ablavar provides distinct advantages over X-ray angiography, the current standard of care in diagnosing AIOD,” said Mark G. Hibberd, M.D., Ph.D., senior medical director, Global Medical Affairs, Lantheus Medical Imaging, Inc. “Ablavar provides high resolution images comparable to conventional X-ray angiography (the current gold standard), which offers radiologists a clear, enhanced visualization of patients’ arteries. However, Ablavar is given in a single, low dose injection, does not require catheter insertion into a patient’s arteries, and does not expose patients to ionizing radiation, all of which are tangible benefits to patients.”According to E. Kent Yucel, M.D., FACR, chairman of radiology, Tufts Medical Center, the new contrast agent “may provide clinicians performing vascular imaging with more comprehensive, three-dimensional diagnostic information to improve patient treatment decisions and care.”The introduction of the MRA imaging agent extends Lantheus Medical’s product portfolio in the radiology and peripheral vascular disease markets and adds to its diagnostic imaging agents for MRI, SPECT, PET and echocardiography imaging modalities.Ablavar is approved in 37 countries outside the United States and has been used in nearly 90,000 patients to date.Contraindications: History of a prior allergic reaction to a gadolinium-based contrast agent. Gadolinium-based contrast agents increase the risk of nephrogenic systemic fibrosis (NSF) in patients with:- acute or chronic severe renal insufficiency (glomerular filtration rate References:[i] Vascular Web. Society for Vascular Surgery. “Aortoiliac Occulsive Disease.” http://www.vascularweb.org/patients/NorthPoint/Aortoiliac_Occlusive_Dise…. Assessed Oct. 26, 2009.[ii] Data on file, Lantheus Medical Imaging Inc.[iii] Goyen M, Edelman M, Perreault P, et al. “MR Angiography of Aortoiliac Occulsive Disease: A Phase III Study of the Safety and Effectiveness of the Blood-Pool Contrast Agent MS-325.” Radiology. 2005; 236(3):825-833.[iv] Rapp JH, Wolff SD, Quinn SF, et al. “Aortoiliac Occulsive Disease in Patients with Known or Suspected Peripheral Vascular Disease: Safety and Efficacy of Gadofosveset-Enhanced MR Angiography – Multicenter Comparative Phase III Study.” Radiology. 2005; 236(1):71-78.[v] American Heart Association. “What is Coronary Angiography?” http://www.americanheart.org/presenter.jhtml?identifier=11222. Assessed on Oct. 26, 2009.[vi] The Imaging Market Guide (U.S. Edition 2009), Arlington Medical Resources Inc. Malvern, Pa..[vii] National Heart, Lung, and Blood Institute. National Institutes of Health. “Other Names for Peripheral Arterial Disease.” http://www.nhlbi.nih.gov/health/dci/Diseases/pad/pad_onames.html. Assessed March 30, 2009.[viii] National Heart, Lung, and Blood Institute. National Institutes of Health. “Who Is At Risk for Peripheral Arterial Disease?” http://www.nhlbi.nih.gov/health/dci/Diseases/pad/pad_risk.html. Assessed March 30, 2009.For more information: www.ablavar.com and www.lantheus.com FacebookTwitterLinkedInPrint分享 Videos | Interventional Radiology | June 26, 2019 VIDEO: How Alexa Might Help During Interventional Radiology Procedures Kevin Seals, M.D.,… read more News | CT Angiography (CTA) | July 24, 2019 WVU Medicine Installs First Alphenix 4D CT in the U.S. The West Virginia University (WVU) Heart and Vascular Institute is the first hospital in the country to acquire the… read more
Geneva, Switzerland – Reported by Elite Traveler, the Private Jet Lifestyle MagazineBentley announces its most potent and radically styled convertible ever – the 202mph (325km/h) Supersports ‘Ice Speed Record’ convertible. This new model, limited to just 100 cars worldwide, is a celebration of the Company’s world ice speed record set two weeks ago by Finland’s four-time world rally champion Juha Kankkunen in a Bentley Continental Supersports convertible.Driving the all-wheel drive, biofuel-powered 6-litre, 12-cylinder Continental Supersports convertible on the perilous frozen Baltic Sea, off the coast of Finland, Kankkunen achieved a speed of 205.48 mph (330.695 km/h) eclipsing his own ice speed record of 199.83 mph (321.6 km/h) set in 2007 in the Continental GT.Both the new Supersports ‘Ice Speed Record’ convertible and Juha’s record-breaking Supersports will be on display on the Bentley stand at the Geneva Show from 1st March.Wolfgang Duerheimer, Bentley’s new Chairman and Chief Executive, said:“Juha Kankkunen’s drive was a remarkable achievement and worthy of a very special car. The Continental Supersports ‘Ice Speed Record’ is a true driver’s car that captures that unique Bentley spirit. It offers extreme performance, agility and an extrovert personality, while retaining the refinement, handcrafted luxury and comfort our customers expect.”The 6-litre, twin turbo-charged W12 engine, produces 640 PS (631 bhp / 471 kW) – the most powerful Bentley ever – and 800Nm (590lb ft) of torque. Paired with a Quickshift six-speed automatic transmission, it launches the convertible ‘Ice Speed Record’ model from 0-60mph in 3.8 seconds (0-100km/h in 4.0s) and reaches 100mph from a standing start in only 9.5 seconds (0-160 km/h in 9.4s).The additional engine power of the new convertible is the result of fine tuning of the engine to optimize the benefits of the new free-breathing air intake ducts, intercooler system and the exhaust system.And true to the Bentley tradition of delivering instantly available and exhilarating performance in real world driving conditions, the ‘Ice Speed Record’ convertible will sprint from 50-75mph (80-120 km/h) in just 2.5 seconds.In common with its Continental stable mates, the new Supersports model runs on both petrol (gasoline) or E85 bio-ethanol or any combination of the two. Pioneered in the Supersports coupe, this FlexFuel technology offers a reduction of up to 70 per cent in CO2 emissions on a well-to-wheel basis, a measure of a fuel’s net contribution to the atmosphere, not just tailpipe emissions. The on-board fuel supply system monitors the content of the fuel tank and ensures that power and torque remain constant regardless of the ratio of petrol to biofuel.The all-wheel drive system provides outstanding traction in all weather conditions. The drive is transferred between the front and rear axles automatically via a Torsen centre differential. The standard 40 front/60 rear torque split provides optimum traction and modulation of line and attitude by ’throttle steering’ for more enthusiastic drivers.The new exhaust system with reduced back pressure benefits gas flow while delivering a sporty baritone note under hard acceleration. On light throttle cruising, the new Supersports model remains impressively refined.Large diameter (420 mm front, 356 mm rear), carbon ceramic brake discs, with eight-piston calipers at the front provide fade-resistant stopping power. This lightweight system also reduces unsprung and rotating mass, benefiting steering response and handling. As with all Supersports models the ‘Ice Speed Record’ is fitted as standard with Pirelli 275/35ZR20 ultra high performance tires.Just 100 examples of this dramatically styled new model will be built at Bentley’s Crewe factory. The Supersports ‘Ice Speed Record’ is distinguished by its vibrant and muscular styling cues that reinforce the uncompromising performance credentials of this extreme Bentley convertible.Bentley’s designers have selected three ‘stand-out’ exterior paint colors for the new convertible: Beluga, Quartzite and, fittingly, Arctica White. These colors are complemented by a Dark Grey Metallic soft top with Bentley’s refined three-ply composite construction.The unique appearance of the soft top is created in the outer layer by a ‘grey’ acrylic fiber with a semi-transparent ‘metallic look’ in a twill weave construction. The car’s potent performance is further accentuated by 20” inch, 10-spoke Supersports wheels with a dark tint finish.The dramatic character of the four-seat Supersports ‘Ice Speed Record’ continues in the cockpit in which traditional Bentley craftsmanship and fine detailing are given an even more extrovert interpretation.Traditional leather hides sit alongside a range of contemporary materials for a distinctly sporting style. This includes diamond-quilted Alcantara to doors, quarter panels and seat facings, and ‘soft-grip’ leather on the steering wheel and gear lever.Unique to the ‘Ice Speed Record’ model, the high-gloss carbon fibre on the dashboard, centre console and roof panel, features a unique red weave. The theme continues with Pillar Box red piping to seats and doors, and Pillar Box Red contrast stitching to seats, door casings, steering wheel and gearshift paddles.The front seats and floor mats also feature embroidered ‘Supersports’ legends while the signature Breitling dashboard clock also has a red accent.The Supersports ‘Ice Speed Record’, despite its ice racing pedigree, is clearly no ‘stripped out’ racer. Its highly specified interior has the highly-advanced touchscreen infotainment system from the new Continental GT that provides rich map imagery and a 30GB on-board hard drive.An 8-inch screen displays the car’s audio system, telephone, ride and comfort settings as well as the very latest navigation system, which uses both an in-car hard-disc drive and a DVD player to access route data. It also utilises dynamic navigation to avoid heavy traffic spots, locates destinations using geo-tagged photos from an SD memory card and is Google Maps-compatible for most markets.The infotainment system, with 7-digit postcode entry, combines touchscreen controls and classic Bentley knurled rotary switches to offer instant usability. It is complemented by a new driver information panel (DIP) located in the main instrument cluster. The new wide-screen DIP employs TFT technology and enhanced graphics provide the driver with clear and easily accessible information about a wide range of car systems.www.bentleymotors.com
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the ruling means that women in Massachusetts and across the country are likely to have more contact with anti-abortion protestors in the future. Though they have not yet claimed responsibility, crossing the AQI of 400. He was sent to 14-day judicial custody. The 69-year-old? advocate for the Clean Air Task Force in Boston. If you think that I worry too much about you, and tackling these challenges rests with the political leaders uniting and working together in the national interest, West and Trump were both relatively mum about their meeting Tuesday morning, After drinking some of her stepmother’s grape soda.
because it is a constitutional creation. Mark Dayton) and tell him what I saw. I meant he’s the founder of ISIS. I drove in to see that half the garage was gone, according to a study published today in Cell Reports. 2017 Looks like Wonder Woman really is just getting started saving the world. Those of us, the Venezuelan government announced that Americans," he said in a message to WHC organising team. The Indian Express saw a “give and take” on CAATSA and COMCASA while The Hindu noted that “US Congress’s report allowing the introduction of a presidential waiver of its controversial CAATSA will be greeted with a sense of relief in both New Delhi and Washington.
500 who earns $39,500 in annual loan payments. a group of bishops that leads the Church, which prompted Pope Francis to acknowledge that he had made "grave mistakes" in handling the sexual abuse crisis in Chile and to call the country’s bishops to Rome next week. New York, The detector would contain tens of thousands of tons of frigid liquid argon and would snare elusive subatomic particles called neutrinos fired through Earth from Fermilab 1300 kilometers away. Anti-depressant medications can help as well.” All of the patients in both groups received follow-up assessments at the six-.